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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNKS
All Species:
14.55
Human Site:
S125
Identified Species:
26.67
UniProt:
O95271
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95271
NP_003738.2
1327
142039
S125
P
N
P
A
G
S
G
S
N
N
S
P
S
S
S
Chimpanzee
Pan troglodytes
XP_001137443
1327
142033
S125
P
N
P
A
G
S
G
S
N
N
S
P
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001090358
1327
142132
S125
P
N
P
A
G
S
G
S
N
N
S
P
S
S
S
Dog
Lupus familis
XP_849388
1327
142003
S125
P
N
P
A
G
G
G
S
N
N
S
P
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_780300
1320
140926
A125
G
N
N
S
A
S
S
A
S
S
P
T
S
S
S
Rat
Rattus norvegicus
NP_001101077
1166
126761
G114
V
N
L
L
L
Q
H
G
A
D
P
N
A
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508887
1320
142724
T137
P
H
S
I
V
D
N
T
E
P
K
K
D
T
I
Chicken
Gallus gallus
Q5F478
990
107379
Frog
Xenopus laevis
NP_001088420
1303
140252
G127
S
N
S
L
S
S
G
G
S
P
S
E
S
P
E
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
R19
L
V
Q
A
I
F
N
R
N
A
D
E
V
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651410
1181
127927
W122
S
P
N
T
T
D
N
W
N
Y
T
P
L
H
E
Honey Bee
Apis mellifera
XP_396483
1166
127309
N114
L
L
L
E
A
G
A
N
P
N
T
R
D
N
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186587
1157
126547
E105
A
C
S
F
G
H
A
E
V
V
V
I
L
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.6
98.9
N.A.
96.5
72.2
N.A.
86.8
23.2
87.1
21.8
N.A.
59.4
62.7
N.A.
63.6
Protein Similarity:
100
99.6
99.7
99.1
N.A.
97
80.3
N.A.
89.1
37.4
90.9
37.3
N.A.
71.7
72.8
N.A.
74.6
P-Site Identity:
100
100
100
93.3
N.A.
33.3
6.6
N.A.
6.6
0
33.3
13.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
60
20
N.A.
26.6
0
40
13.3
N.A.
20
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
39
16
0
16
8
8
8
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
0
0
0
8
8
0
16
0
8
% D
% Glu:
0
0
0
8
0
0
0
8
8
0
0
16
0
0
16
% E
% Phe:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
39
16
39
16
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
8
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% K
% Leu:
16
8
16
16
8
0
0
0
0
0
0
0
16
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
54
16
0
0
0
24
8
47
39
0
8
0
8
0
% N
% Pro:
39
8
31
0
0
0
0
0
8
16
16
39
0
8
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
8
% R
% Ser:
16
0
24
8
8
39
8
31
16
8
39
0
47
39
39
% S
% Thr:
0
0
0
8
8
0
0
8
0
0
16
8
0
8
0
% T
% Val:
8
8
0
0
8
0
0
0
8
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _